Friday, May 23, 2008

Two studies, which is the better choice?

Generally speaking and without much consideration o a comparison between these two studies, I'd opt for diet and exercise for the best benefit, initially and over the long term.

We know that for most cases of Type 2, Diabetes is a nutritional health problem.

Historically many cases developed from the time when whole grains began to be processed, removing the health promoting 'germ' of these grains.

Over processing foods and more environmental factors add to the mix.

Type I is often connected with the Hepatitis vaccine and other things that relate to immune stress. Recently, vitamin D (3) has shown very helpful. Older research shows that marshmallow root and astrgalus help mediate this problem.

In today's medicine, insulin is generally genetically engineered and this process may contribute to health problems.

Easier to eat a wholesome diet and exercise that rely on injections.

Managing monitoring is also something that cannot be over stressed, 5-6 checks a day of bllod sugar beats once or after meals.
Diet, exercise can delay diabetes for years: study
By Michael Kahn
Thu May 22, 2008

Drinking less alcohol, eating more vegetables and exercising can prevent or delay the onset of diabetes, researchers said on Friday in a study showing that lifestyle changes can make a big difference.

Diet and exercise reduced the incidence of diabetes by about 43 percent over 20 years among 577 high-risk Chinese adults, the researchers reported in the journal Lancet.

At the end of the 20 years, 80 percent of those who changed what they ate and exercised more had diabetes, compared with 93 percent who made no changes, said Guangwei Li of the China-Japan Friendship Hospital in Beijing and Ping Zhang at the U.S. Centers for Disease Control and Prevention.

The findings came as part of a series of studies addressing new research about diabetes, which affects 246 million adults worldwide, and accounts for 6 percent of all global deaths.

"The challenge is to translate research findings into substantial clinical improvements for patients. Although prospects are hopeful, they are not assured," the Lancet wrote in a commentary.

Type 2 diabetes accounts for about 90 percent of all diabetes cases and is closely linked to obesity and physical inactivity. Type 1 diabetes is an auto-immune disease often diagnosed at an early age.

The International Diabetes Federation estimates more than 380 million people will have a form of diabetes by 2025 as more developing nations adopt a Western lifestyle.

The researchers followed 577 Chinese adults at risk of diabetes over a 20-year period to see how prodding people to change their lifestyles could affect their health.

The volunteers were assigned to either a control group or one of three groups that included an improved diet, better exercise or a combination of both.

The researchers did not say what specific foods or amount of exercise contributed to the health improvements but said the findings provide an effective strategy to deal with a disease that kills about 3 million people worldwide each year.

"This study has shown that ... group-based interventions targeting lifestyle changes such as diet and exercise produce a durable and long-lasting reduction in incidence of type 2 diabetes," the researchers wrote.

Another team reported that insulin infusions or multiple daily injections given early to people with newly diagnosed type 2 diabetes helped the body's insulin-producing cells and restored blood sugar control faster than standard pills.

Too much glucose, or blood sugar, in the blood -- a hallmark of diabetes -- can damage the eyes and kidneys, and also leads to heart disease, stroke and limb amputations.

(Reporting by Michael Kahn; Editing by Maggie Fox and David Fogarty)
Copyright © 2008 Reuters Limited.


Act early to blunt long-term impact of diabetes: study Thu May 22, 2008

Aggressive insulin treatment or lifestyle changes at the onset of diabetes can sharply curb the incidence and impact of the disease over the long haul, according to two studies released Friday.

Intensive insulin therapy through daily injections for Type 2 diabetes, which affects some 250 million people worldwide, is typically started late in the course of the disease.

But researchers in China found that if this treatment is undertaken before the body loses the ability to control sugar levels in the blood -- a condition known as glycaemia -- patients recover normal levels faster and are less at risk of remission.

Type 2 diabetes can cause conditions ranging from kidney failure to blindness and heart disease, and complications can lead to death.

The condition, strongly linked to obesity, occurs when the liver fails to produce enough insulin or becomes resistant to the hormone, which controls blood sugar levels.

A team led by Jianping Weng of Sun Yat-Sen University in Guangzhou divided nearly 400 patients aged 25 to 70 with Type 2 diabetes into three groups.

Two received intensive insulin therapy, either through an under-the-skin drip or multiple daily injections. The third was given standard oral diabetic drugs.

Treatment was stopped when regular blood glucose control had been restored for two weeks, after which patients regulated sugar levels through diet and exercise alone.

The study, published in the British journal The Lancet, found that more patients in the two insulin-intensive groups hit normal levels, and did so faster, in four to six days rather than nine, compared to the control group.

As significant, remission rates -- the number of patients whose blood sugar remained at acceptable levels -- were nearly twice as high in the first two groups.

The second study, led by Guangwei Li of the China-Japan Friendship Hospital in Beijing and also published in The Lancet, showed that a controlled diet and exercise over six years prevented or delayed diabetes onset by up to an additional 14 years.

Previous studies have shown the efficacy of lifestyle changes in controlling diabetes, but questions remained on the long-term impact.

Li found that a monitored diet coupled with physical activity halved the incidence of diabetes during the six years of intervention, and by 43 percent over 20 years.

Type 2 diabetes has become rampant in both developed and developing countries as a result of traditional diets being abandoned for processed and junk foods and people getting less exercise. Once a disease that affected only adults, it has become common among obese adolescents as well.

The International Diabetes Federation forecasts the number of cases -- including many adolescents -- will explode from 246 million today to 380 million by 2025.

A less common form of diabetes called Type 1 is caused by permanent destruction of insulin-producing beta cells in the pancreas, and usually occurs early in life. It is lethal unless treated with insulin.

Copyright © 2008 Agence France Presse.

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