Saturday, December 12, 2009

Help Prevent Colon Cancer: Hope for Whole Health

Natural Health News has at least 20 posts related to vitamins and other help that is protective for colon cancer.

Now another article relives us from the negative hype about vitamin supplements and cancer that you have heard now for at least a decade.
Selenium, Omega-3s May Stave Off Colorectal Cancer

HealthDay Reporter by Jennifer Thomas
TUESDAY, Dec. 8 (HealthDay News) -- Certain dietary supplements appear to affect the development of colorectal cancer or its recurrence, two new studies suggest.

In one study, researchers from the U.S. National Institute for Environmental Health Sciences found that eating a diet high in omega-3 fatty acids cut the risk of developing colorectal cancer by nearly 40 percent. In the other study, from cancer researchers in Italy, consumption of a dietary supplement containing selenium was found to reduce the chances of having polyps recur by a similar amount.

Both studies were to be presented Dec. 7 in Houston at a conference on cancer prevention sponsored by the American Association for Cancer Research.

In the selenium study, 411 people, 25 to 75 years old, who'd had one or more colorectal polyps removed took either a supplement or a placebo. The supplement, described as an antioxidant compound, contained 200 micrograms of selenomethionnine (a combination of selenium and methionnine - Our Note: This is the best form of selenium according to the most currant science), 30 milligrams of zinc, 6,000 international units of vitamin A, 180 milligrams of vitamin C and 30 milligrams of vitamin E.

Participants had a colonoscopy one year, three years and five years after starting the regimen.

Polyps recurred in 4.2 percent of those taking the supplement, compared with 7.2 percent of the placebo group. Overall, the study found, people taking the supplement had about a 40 percent reduction in risk for a return of polyps.

The researchers estimated that, after 15 years, about 48 percent of those taking the supplement would still be free of polyps, versus about 30 percent of those not taking the supplement.

Polyps, or adenoma, are benign growths on the large bowel. Though only a small proportion progress to become cancer, about 70 to 80 percent of colorectal cancer cases begin as polyps, according to the American Association for Cancer Research. About one in four people, most older than 60, will have at least one adenoma.

Selenium is found in soil (Our Note: Western US states bordering Canada are known to be severely low in selenium and as such has a negative impact on thyroid function.), and human consumption comes by eating plants that have absorbed the nutrient or fish or animals that have eaten plants as part of their diet. "The content of selenium in the food depends on the soil content of this trace element, and in the same country there are areas at high, adequate or low content of selenium in the soil," said the study's lead author, Dr. Luigina Bonelli, head of the unit of secondary prevention and screening at the National Institute for Cancer Research in Genoa, Italy.

Earlier research had suggested that selenium can inhibit cell proliferation in the colon and rectum, Bonelli said.

Michele Forman, a professor of epidemiology at the M.D. Anderson Cancer Center in Houston, said that, though the findings are interesting, it's impossible to tell if the benefit was attributable to the selenium or to the other vitamins and minerals included in the supplement.

"You really don't know if it's the selenium or some combination that reduces risk of recurrence," Forman said.

In addition, the daily dosages of vitamins A and E taken by the participants were higher than the recommended daily allowances, Forman added. High levels of such vitamins can be detrimental, she said. (Our note: Not all supplements at high dose levels are harmful.)

In the omega-3 study, U.S. researchers surveyed 1,509 whites and 369 blacks about their dietary habits in the past year. About half of the participants had colorectal cancer.

Among the white participants, those whose diets were in the highest fourth of omega-3 fatty acid consumption were 39 percent less likely to have colorectal cancer than those in the lowest fourth. However, for reasons the authors said they did not know, no association was noted between omega-3s and a reduction of colorectal cancer risk among black participants. The disease occurs at a higher rate among blacks than whites.
"Our finding clearly supports the evidence from previous experimental and clinical studies showing that long-chain omega-3 fatty acids inhibit tumor growth," said the study's lead author, Sangmi Kim, a postdoctoral fellow at the U.S. National Institute of Environmental Health Sciences in Research Triangle Park, N.C.
Kim said the research supports boosting omega-3 intake through diet or perhaps by taking an omega-3 supplement. Omega-3 fatty acids are found in fish, especially oily fish such as salmon, mackerel, herring, anchovies, sardines and tuna. Plant-based sources include flax and flaxseed oil, Brussels sprouts, soybeans and (soybean oil, canola oil - NOTE: We suggest you avoide both these oils), spinach, walnuts and kiwi.

Previous studies have suggested that omega-3 fatty acids act as anti-inflammatory agents and help prevent cancer. But in the new study, Forman noted, participants were asked about their diets after they had been diagnosed with colorectal cancer so it's possible that their recollections were not fully accurate.

In addition, she said, it's possible that the benefit was not the result of omega-3s. Those who ate more fish might have had a healthier diet overall, she said.

"Were they eating a salmon-and-broccoli diet or a hamburger-and-french-fry diet?" Forman asked. "We don't know enough to say that it's truly the effect of the omega-3s."

Our Note:  We beleive that the dose levels in the supplement mentioned in this areticle is well below therapeutic levels.
While I am not an institutionalized thinker, I am in support of those who have tried to help make more people aware of the role of nursing, probably a truly wholistic profession on its own. I would like to see the same support from the organizationally based groups to the work we do.

I will say however that I support this comment from the AHNA:
The American Holistic Nurses Association (AHNA) has formally requested that US Senator Tom Harkin (D-IA) not move to re-name the NIH National Center for Complementary and Alternative Medicine (NCCAM) the "National Center for Integrative Medicine." Harkin brought up the idea of the name change in public comments surrounding the Institute of Medicine Summit in February of this year. In a letter co-signed by 23 other nursing organizations, the AHNA wrote:
"There are so many in this country who enthusiastically support a vision to put integrative health care at the heart of national health reform. However, to facilitate this vision; to reinforce a more inclusive, representative, and collaborative partnering of every health and health-related profession and constituency; and to recognize and maximize the valuable contributions of all, we would like to suggest the renaming of the National Center for Complementary and Alterative Medicine to the National Center for Integrative Health and Healthcare. In transforming the health care paradigm, a shift in language can be a critical influence in supporting and adopting that change. The use of Integrative Health and Healthcare focuses on people’s health and well-being, rather than on a specific profession, and broadens the array of disciplines involved in promoting it."

As of this writing, Harkin had not formally responded to the nurses nor had an Integrator query to Harkin's staff elicited a response.
I do not support the use of the terms "integrative" or "complementary" in regard to health care.  I believe this promotes more separation from what used to be quite common, the "team" approach. And I believe it further sets up barriers to health and limits access both for providers but for patients.

In the classes I taught in the Pueget Sound area for so many years, always, in my discussion of vitamin E, its protective benefit for colon cancer was always noted.
See "Vitamins Enhance Chemotherapy" from leaflady.org

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